5550 Warren PkwyFrisco, TX 75034
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Platelet-Rich Plasma (PRP) Therapy

Whole blood is composed of three primary constituents: Red Blood Cells (RBCs), White Blood Cells (WBCs), and Plasma. The function of the RBCs is to carry and transport oxygen (they are important for endurance athletes). WBCs fight infection. Diseases like leukemia, lymphoma, and HIV stem from problems with the WBC. Within the plasma are small cells called platelets. The platelets are best known for their importance in clotting blood. However, platelets also contain hundreds of proteins called growth factors which are critically important in the healing of injuries.

PRP is plasma with many more platelets than what is typically found in whole blood. By drawing whole blood and putting it through a centrifugation process, we are able to concentrate the platelets. The concentration of platelets — and, thereby, the concentration of growth factors — can be 5 to 10 times greater (or richer) than usual.

To develop a PRP preparation, blood must first be drawn from a patient (usually between 30 and 60cc of whole blood). The platelets are separated from the other blood cells and their concentration is increased during a process called centrifugation (ie. spinning the blood). The final PRP product is separated and injected back into the patient at the source of injury, ultimately augmenting the natural healing response of the body while expediting recovery.

What Conditions Are Treated With PRP? Is It Effective?

PRP has been studied extensively over the past few years. There are hundreds of studies published that review its effectiveness and compare it to previously used “gold standards” (ex. corticosteroids). PRP has been shown to be effective for these conditions and many others:

  • Chronic Tendon Injuries (ex. Tennis Elbow, Golfer’s Elbow, Jumper’s Knee (Patella Tendinitis))
  • Acute Tendon, Ligament, and Muscle Injuries (ex. Achilles Tendon Injuries)
  • Osteoarthritis (Knee, Hip, Shoulder, etc)
  • Rotator Cuff tears in the shoulder
  • Bursitis (Hip, Knee, Shoulder)
Studies Supporting the use of PRP:
Tendinopathy and Tendonitis of the Elbow:
Hip Conditions: Tendinopathy and Bursitis
Hip Conditions: Tendinopathy and Bursitis

Dr. Dold is widely considered an expert in PRP and other biologic therapies. These treatments are minimally invasive and can be performed in clinic, often negating the need for surgery. If you are considering PRP as a treatment option for you, please contact us for a consultation: 469.850.0680.


Another treatment option is a procedure called viscosupplementation. If you have tried all other nonsurgical treatment methods and your pain continues to limit your activities, viscosupplementation may be an option.

In this procedure, a gel-like fluid called hyaluronic acid is injected into the knee joint. Hyaluronic acid is a naturally occurring substance found in the synovial fluid surrounding joints. It acts as a lubricant to enable bones to move smoothly over each other and as a shock absorber for joint loads. People with osteoarthritis have a lower-than-normal concentration of hyaluronic acid in their joints. The theory is that adding hyaluronic acid to the arthritic joint will facilitate movement and reduce pain.

The most recent research, however, has not found viscosupplementation to be effective at significantly reducing pain or improving function. Although some patients report pain relief with the procedure, some people are not helped by the injections.


Adipose-Derived Mesenchymal Stem Cells

The two primary sources of mesenchymal stem cells (MSCs) are our bone marrow and adipose tissue (ie. fat!). Adipose tissue (that’s right, the fat around our abdomen) is a rich source of these regenerative MSCs and can be harvested to produce a solution used to heal injuries and regenerate tissue. The lipoaspirate procedure is performed in clinic under local anesthetic. The entire procedure is usually performed in under and hour. Adipose tissue is typically harvested from the abdominal area and is then concentrated in a specialized centrifuge to produce a mesenchymal stem cell graft or solution that is injected at the desired site of treatment (ex. knee joint, rotator cuff, Achilles tendon, etc). Adipose-derived stem cells (ASCs) provide a promising future in the field of tissue engineering and regenerative medicine. Due to their wide availability and ability to differentiate into other tissue types of the musculoskeletal system, including bone, cartilage, muscle, and tendon, ASCs may serve a wide variety of applications. In comparison to bone marrow-derived stem cells, the amount of ASCs is roughly 500-fold greater when isolated from an equivalent amount of adipose tissue. Why not use this unwanted tissue for something good?!

Contact Dr. Dold to see if you are a candidate for a lipoaspirate procedure which might help you avoid surgery.

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